Authorities are investigating a deadly UPS cargo plane crash near Louisville Muhammad Ali International Airport that killed 12 people. Early findings show the left engine of the MD-11F detached during takeoff on November 4, 2025, sending the aircraft crashing just beyond the runway and igniting massive fires. NTSB spokesperson Todd Inman said the plane, bound for Honolulu, “lifted off and cleared the fence, but shortly after struck terrain off airport property.”

The five-ton engine was hurled across the runway, possibly damaging the right wing and causing loss of control. Investigators recovered the plane’s black boxes, and CCTV footage confirmed the engine detachment. Louisville Mayor Craig Greenberg identified the victims as three crew members and nine others nearby. Fifteen families have sought help at a reunification center. The FAA joined the NTSB in examining potential maintenance or mechanical issues.

Kentucky Governor Andy Beshear urged prayers and warned residents to follow shelter-in-place orders due to hazardous debris. Dozens of fire and rescue agencies responded, battling flames that engulfed nearby businesses, including Kentucky Patrol and Recycling and Grade A Autoparts. LG&E reported minor power damage, while local plants and the Convention Center paused operations for safety checks.

Witnesses described seeing the plane flying unusually low before exploding in a fireball. Flights were suspended as thick black smoke rose over Louisville. Community leaders and the Muhammad Ali Center offered condolences and praised first responders. The investigation continues as families await answers in the wake of this tragic disaster.